Bibliometric evaluation of the scientific production on estrogen hormone therapy during menopause

Estrogen hormone therapy is a widely used treatment option to alleviate climacteric symptoms in menopausal women. However, its use remains controversial due to potential adverse effects. In this context, the aim of this study was to analyze the bibliometric characteristics of scientific publications on estrogen hormone therapy during menopause. A bibliometric, observational, descriptive, and retrospective study was carried out using publications indexed in Scopus between 2019 and 2024. The search strategy was developed using MeSH terms and Boolean operators. A total of 947 articles were identified, of which 511 met the inclusion and exclusion criteria and were analyzed. Bibliometric trends and collaboration networks were assessed using SciVal and VOSviewer. The analysis revealed a slight increase in scientific output on estrogen hormone therapy during menopause, with a notable predominance of publications in high-impact journals such as Menopause. The United States led in the number of publications and international collaborations, although domestic collaborations were more common. Harvard University and Brigham and Women’s Hospital stood out as the most productive institutions, while Virginia M. Miller was identified as the most prolific author. In recent years, scientific production on estrogen hormone therapy has grown, with a concentration in high-impact journals and significant contributions from US institutions and authors. While international collaboration exists, there are still opportunities to expand global research partnerships further.