Abstract
Breast cancer consists of a heterogeneous group of tumors with different features, biology and treatments. Cancer stem cells (CSCs) have been associated with an aggressive cellular behavior, resistance to chemotherapy and radiotherapy in many types of neoplasms, and a strong correlation between prominin-1 (CD133) expression in cancer stem cells from different types of cancer exist. A discussion is presented on recent immunotherapeutic strategies that target CD133 in breast CSCs. Furthermore, it is suggested that immunotherapy targeting CD133 breast CSCs and/or in combination with other current treatments result in a better outcome.
| Original language | English |
|---|---|
| Pages (from-to) | 22-30 |
| Number of pages | 9 |
| Journal | Gaceta Mexicana de Oncologia |
| Volume | 15 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1 Jan 2016 |
| Externally published | Yes |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Breast cancer
- CD133
- CSCs
- Immunotherapy
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