TY - CHAP
T1 - Virome and Microbiome Interaction and Their Implication in the Human Gut Health
AU - Abonahas, Hebatallah H.
AU - El-Maradny, Yousra A.
AU - Gezaf, Sara A.
AU - Abo Nouh, Fatma A.
AU - Abonahas, Yousef H.
AU - Landa-Acuña, Daniela
AU - Gil-Polo, Alejandra
AU - Saied, Essa M.
AU - Abdel-Azeem, Ahmed M.
N1 - Publisher Copyright:
© The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2022, corrected publication 2022.
PY - 2022/1/1
Y1 - 2022/1/1
N2 - As a complex ecosystem, human gut microbiota have several functions integrated in the host organism through various activities including metabolism, immunity, absorption, etc. One of the human microbiota is viruses, whose composition has not been completely described up till now. Vaious studies proved that the human gut harbors different types of viruses like plant-derived viruses, giant viruses, and bacteriophages. Recently metagenomic methods have allowed to reconstitute entire viral genomes from the genetic material spread in the human gut, opening new avenue on the understanding of the gut virome composition, the importance of gut microbiome, and potential clinical applications. This chapter aims to shed light on the latest evidence on human gut “virome” composition, interaction, its function, and possible future therapeutic applications in human health.
AB - As a complex ecosystem, human gut microbiota have several functions integrated in the host organism through various activities including metabolism, immunity, absorption, etc. One of the human microbiota is viruses, whose composition has not been completely described up till now. Vaious studies proved that the human gut harbors different types of viruses like plant-derived viruses, giant viruses, and bacteriophages. Recently metagenomic methods have allowed to reconstitute entire viral genomes from the genetic material spread in the human gut, opening new avenue on the understanding of the gut virome composition, the importance of gut microbiome, and potential clinical applications. This chapter aims to shed light on the latest evidence on human gut “virome” composition, interaction, its function, and possible future therapeutic applications in human health.
KW - Bacteriophages
KW - Diabetes
KW - Gut microbiome
KW - Homeostasis
KW - Obesity
UR - http://www.scopus.com/inward/record.url?scp=85153425281&partnerID=8YFLogxK
U2 - 10.1007/978-981-16-1626-6_4
DO - 10.1007/978-981-16-1626-6_4
M3 - Chapter
AN - SCOPUS:85153425281
SN - 9789811616259
SP - 97
EP - 138
BT - Microbiome-Gut-Brain Axis
PB - Springer Nature
ER -
